Animal copy scientific studies haven't been carried out With all the drug mix-promethazine and codeine. It isn't known whether this drug combination might cause fetal harm when administered to your pregnant girl or can impact copy capacity.
Promethazine HCl Oral Resolution is contraindicated in comatose states, As well as in men and women known being hypersensitive or to have had an idiosyncratic response to promethazine or to other phenothiazines.
Sedation in each youngsters and adults, as well as relief of apprehension and creation of gentle sleep from which the patient is usually simply aroused.
Avoidance and Charge of nausea and vomiting connected with selected different types of anesthesia and operation.
Promethazine HCl Oral Answer must be applied with warning in clients with bone-marrow despair. Leukopenia and agranulocytosis are actually reported, generally when Promethazine (Promethazine HCl) is Utilized in association with other recognized marrow-toxic brokers.
Codeine may perhaps increase the neuromuscular blocking action of skeletal muscle mass relaxants and create a heightened diploma of respiratory depression.
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Phenothiazines are connected with dystonic reactions, significantly in pediatric individuals which have an acute sickness connected to dehydration. Paradoxical reactions, such as dystonia, torticollis, tongue protrusion, hyperexcitability, and abnormal actions have been noted in clients next just one administration of promethazine. Discontinue Promethazine HCl and Codeine Phosphate Oral Resolution if a paradoxical response takes place.
We foresee reposting the pictures as soon as we are in a position establish and filter out visuals that don't match the information supplied in the drug labels. NDC Codes
Avoidance and Charge of nausea and vomiting affiliated with certain varieties of anesthesia and operation.
Propulsive peristaltic waves inside the colon are diminished, though tone might be enhanced to The more info purpose of spasm causing constipation. Other opioid-induced consequences may consist of a reduction in biliary and pancreatic secretions, spasm of sphincter of Oddi, and transient elevations in serum amylase.
Stimulation might be obvious, specifically in little ones and geriatric clients. Convulsions may possibly hardly ever take place. A paradoxical-kind response has long been described in young children getting single doses of seventy five mg to one hundred twenty five mg orally, characterised by hyperexcitability and nightmares.
Respiratory despair bringing about arrest, coma, and Demise has transpired with the use of codeine antitussives in younger young children, especially during the beneath-one-yr infants whose power to deactivate the drug just isn't absolutely produced.
Promethazine Symptoms and indications of overdosage with promethazine range between delicate melancholy in the central nervous system and cardiovascular system to profound hypotension, respiratory despair, unconsciousness and sudden death.